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The effect of gravity on liquid plug propagation in a two-dimensional channel

REA Auditado

The effect of plug propagation speed and gravity on the quasisteady motion of a liquid plug in a two-dimensional liquid-lined channel oriented at an angle α with respect to gravity is studied. The problem is motivated by the transport of liquid plugs instilled into pulmonary airways in medical treatments such as surfactant replacement therapy, drug delivery, and liquid ventilation. The capillary number Ca is assumed to be small, while the Bond number Bo is arbitrary.

Tema: general: 

• Ciencias

Yohimbine-Induced Amygdala Activation in Pathological Gamblers: A Pilot Study

REA Auditado

Rationale and Objectives: There is evidence that drug addiction is associated with increased physiological and psychological responses to stress. In this pilot functional magnetic resonance imaging (fMRI) study we assessed whether a prototype behavioral addiction, pathological gambling (PG), is likewise associated with an enhanced response to stress.

Tema: general: 

• Ciencias de la Salud›Medicina

RB1 gene mutation up-date, a meta-analysis based on 932 reported mutations available in a searchable database

REA Auditado

[Background] Retinoblastoma, a prototype of hereditary cancer, is the most common intraocular tumour in children and potential cause of blindness from therapeutic eye ablation, second tumours in germ line carrier's survivors, and even death when left untreated. The molecular scanning of RB1 in search of germ line mutations lead to the publication of more than 900 mutations whose knowledge is important for genetic counselling and the characterization of phenotypic-genotypic relationships. [Results] A searchable database (RBGMdb) has been constructed with 932 published RB1 mutations.

Tema: general: 

• Ciencias