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Multi-level model for the investigation of oncoantigen-driven vaccination effect

REA Auditado

Abstract Background Cancer stem cell theory suggests that cancers are derived by a population of cells named Cancer Stem Cells (CSCs) that are involved in the growth and in the progression of tumors, and lead to a hierarchical structure characterized by differentiated cell population.

Tema: general: 

• Ciencias›Biología

An un-commissioned randomized, placebo-controlled double-blind study to test the effect of deep sea fish oil as a pain reliever for dogs suffering from canine OA

REA Auditado

Abstract Background An un-commissioned randomized, double-blinded, placebo controlled clinical study was planned using a deep sea fish oil product for pets. Seventy-seven client-owned dogs with osteoarthritis were randomly assigned to supplement the food with either the fish oil product or corn (=placebo) oil. Our main outcome variables were force platform variables peak vertical force (PVF) and impulse, the validated Helsinki Chronic Pain Index (HCPI) and the use of rescue NSAIDs.

Tema: general: 

• Ciencias›Biología

The effect of training set on the classification of honey bee gut microbiota using the Naïve Bayesian Classifier

REA Auditado

Abstract Background Microbial ecologists now routinely utilize next-generation sequencing methods to assess microbial diversity in the environment. One tool heavily utilized by many groups is the Naïve Bayesian Classifier developed by the Ribosomal Database Project (RDP-NBC).

Tema: general: 

• Ciencias›Biología

New methods for separating causes from effects in genomics data

REA Auditado

Abstract Background The discovery of molecular pathways is a challenging problem and its solution relies on the identification of causal molecular interactions in genomics data. Causal molecular interactions can be discovered using randomized experiments; however such experiments are often costly, infeasible, or unethical.

Tema: general: 

• Ciencias›Biología

Effects of proactive population-based nephrologist oversight on progression of chronic kidney disease: a retrospective control analysis

REA Auditado

Abstract Background Benefits of early nephrology care are well-established, but as many as 40% of U.S. patients with end-stage renal disease (ESRD) do not see a nephrologist before its onset. Our objective was to evaluate the effect of proactive, population-based nephrologist oversight (PPNO) on chronic kidney disease (CKD) progression. Methods Retrospective control analysis of Kaiser Permanente Hawaii members with CKD using propensity score matching methods.

Tema: general: 

• Ciencias de la Salud›Medicina

Profiling the different needs and expectations of patients for population-based medicine: a case study using segmentation analysis

REA Auditado

Abstract Background This study illustrates an evidence-based method for the segmentation analysis of patients that could greatly improve the approach to population-based medicine, by filling a gap in the empirical analysis of this topic. Segmentation facilitates individual patient care in the context of the culture, health status, and the health needs of the entire population to which that patient belongs.

Tema: general: 

• Ciencias de la Salud›Medicina

Mapping of multiple criteria for priority setting of health interventions: an aid for decision makers

REA Auditado

Abstract Background In rationing decisions in health, many criteria like costs, effectiveness, equity and feasibility concerns play a role. These criteria stem from different disciplines that all aim to inform health care rationing decisions, but a single underlying concept that incorporates all criteria does not yet exist. Therefore, we aim to develop a conceptual mapping of criteria, based on the World Health Organization’s Health Systems Performance and Health Systems Building Blocks frameworks.

Tema: general: 

• Ciencias de la Salud›Medicina

Catastrophic health care spending and impoverishment in Kenya

REA Auditado

Abstract Background Many health systems in Africa are funded primarily through out-of-pocket payments. Out-of-pocket payments prevent people from seeking care, can result to catastrophic health spending and lead to impoverishment.

Tema: general: 

• Ciencias de la Salud›Medicina

The retention of health human resources in primary healthcare centers in Lebanon: a national survey

REA Auditado

Abstract Background Critical shortages of health human resources (HHR), associated with high turnover rates, have been a concern in many countries around the globe. Of particular interest is the effect of such a trend on the primary healthcare (PHC) sector; considered a cornerstone in any effective healthcare system.

Tema: general: 

• Ciencias de la Salud›Medicina

Cattle producers’ perceptions of biosecurity

REA Auditado

Abstract Background The limited use of biosecurity practices by many in the farming community is likely to be due to a range of factors; further understanding of this issue is required.

Tema: general: 

• Ciencias›Biología