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Decrease of blood pressure by community-based strategies

REA Auditado

In a cross section study performed in Rauch in 1997 we found a high prevalence of hypertension and low levels of treatment and control. To evaluate the impact of the community-based intervention activities on blood pressure (BP), we made a cohort study in 1526 inhabitants aged between 15 and 75 years in 2003. The initial study, the advice to consult the family doctor when alterations were found, the free provision of antihypertensive drugs, the press diffusion of the study results and a healthy lifestyle were included among the intervention activities.

Tema: general: 

• Ciencias de la Salud›Medicina›Medicina (en General)

Effect of hypercortisolism control on high blood pressure in Cushing's syndrome

REA Auditado

Many hypertensive patients affected by endogenous Cushing's syndrome (CS) persist with high blood pressure (HBP) despite good control of cortisol excess. We assessed the effect of preoperative ketoconazole administration and of definitive treatment of CS on arterial hypertension and analysed the factors involved in the persistence of hypertension. We assessed retrospectively 71 patients with CS and HBP (60 women, 11 men; 50 pituitary, 21 adrenal) successfully treated by surgery and/or radiotherapy; 19 of them received ketoconazole (KNZ) before surgery.

Tema: general: 

• Ciencias de la Salud›Medicina›Medicina (en General)

Transient expiratory flow interruptions (TEFI) increase expiratory flow in acute asthma exacerbation

REA Auditado

We have shown that expiratory flows increase when expirations are rapidly interrupted in stable asthmatic patients. We hypothesized that a similar increase could be obtained in patients with acute exacerbation of bronchial asthma treated in the Emergency Room. A total of 30 asthmatic patients were randomly allocated into two groups, the study and the control groups. Patients in the study group were connected to a device with an inspiratory line designed to administer pressurized aerosols.

Tema: general: 

• Ciencias de la Salud›Medicina›Medicina (en General)

In what clinical settings should Cushing´s syndrome be suspected?

REA Auditado

Despite its low frequency, endogenous Cushing's syndrome is not an exceptional clinical entity. A growing number of cases are currently derived to specialized centers suggesting an increasing knowledge of the clinical features of hypercortisolism by specialists of diverse branches of clinical medicine. Clinical signs derive from an exaggeration of the physiological actions of cortisol inducing protein breakdown, hyperglycemia, fat mobilization, dyslipidemia, hydrosaline retention, immunosuppression and increased susceptibility to infection.

Tema: general: 

• Ciencias de la Salud›Medicina›Medicina (en General)

General physicians and the management of heart failure in an Argentine population

REA Auditado

The aim of this study was to assess how general physicians (GP) think that heart failure (HF) should be managed and how they implement their knowledge. It was conducted in Buenos Aires City and suburban area, with the collaboration of 5 cardiologists, and 29 GP who were selected randomly, and were asked to keep a log of all patients they saw with HF. The methodology was similar to that employed in an international initiative named"Improvement" already performed in Europe. Data were obtained of 220 note patients.

Tema: general: 

• Ciencias de la Salud›Medicina›Medicina (en General)

Glomerular filtration rate, cardiovascular risk factors and insulin resistance

REA Auditado

The aim of this paper was to study the estimated glomerular filtration rate (eGFR), its changes with age, and its association with systolic blood pressure (SBP) and diastolic BP (DBP), indicators of obesity, dyslipemia, insulin resistance and inflammation on a random population sample. BP, weight, size and waist circumference (WC) were recorded at home. Fasting morning blood samples were analysed. The eGFR was calculated with MDRD (eGFR-MDRD), Cockroft-Gault (eGFR-CG) adjusted to 1.73 m² and reciprocal of serum creatinine (100/serum cretinine).

Tema: general: 

• Ciencias de la Salud›Medicina›Medicina (en General)

Alanine-aminotransferase: an early marker for insulin resistance?

REA Auditado

In a population-based sample, after excluding alcohol consumption, hepatotoxic drugs and hepatitis Band C infected, we investigated if alanine-aminotransferase (ALT) was associated with metabolic syndrome and insulin resistance, and if this association was caused by non-alcoholic fatty liver disease (NAFLD). The sample (432 female and 119 male) was divided into two ALT thresholds corresponding to the 50th and 75th percentiles (P) (female ≤ 15 and ≤ 19 U/L; male ≤ 17 and ≤ 23 U/l, respectively).

Tema: general: 

• Ciencias de la Salud›Medicina›Medicina (en General)

Adult growth hormone deficiency metabolic alterations and evaluation of different risk groups

REA Auditado

Adult growth hormone deficiency (AGHD) is an heterogeneous clinical entity characterized by increased cardiovascular morbidity and mortality, alterations in body composition, osteoporosis and impaired quality of life. In order to characterize higher risk subpopulations we studied 77 patients with AGHD, 35 with childhood onset (AGHD-CO): CA 18-44 yr.; 13 females and 22 males, and 42 with adult onset (AGHD-AO): CA 25-70 yr.; 22 females and 20 males. IGF-I, lipid profile, glycemia and glycosylated hemoglobin were measured.

Tema: general: 

• Ciencias de la Salud›Medicina›Medicina (en General)